[3] A small amount may also be used for emergency disinfection of drinking water. [3][4] Taken by mouth it is used to treat thyrotoxicosis until surgery can be carried out, protect the thyroid gland from radioactive iodine, and to treat iodine deficiency. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. [11] In the case of benzyl alcohols and alcohols with α-carbonyl groups, reduction by HI can provide synthetically useful yields of the corresponding hydrocarbon product (ROH + 2HI → RH + H2O + I2). Large volumes of concentrations more than 2.2% may be subject to regulation. Aqueous Iodine Solution is used for Fungal skin infection, Respiratory problems, Radiation emergency associated with the use of radioactive iodides, Hyperthyroidism, Leg ulcers and other conditions. [4], CS1 maint: BOT: original-url status unknown (, World Health Organization's List of Essential Medicines, "Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies", "Final Rule: Changes in the Regulation of Iodine Crystals and Chemical Mixtures Containing Over 2.2 Percent Iodine", "Effect of lugol solution on thyroid gland blood flow and microvessel density in the patients with Graves' disease", "Effect of preoperative iodine in patients with Graves' disease controlled with antithyroid drugs and thyroxine", "JAK TO Z CZARNOBYLEM BYŁO - ZBIGNIEW JAWORSKI - Wiedza i Życie - 5/1996", "Acute toxic gastric mucosal damage induced by Lugol's iodine spray during chromoendoscopy", "Material Safety Data Sheet Iodine Solution, 5% MSDS", "Chernobyl: the Biggest BLUFF of the 20th Century", US DEA, "Final Rule: Changes in the Regulation of Iodine Crystals and Chemical Mixtures Containing Over 2.2 Percent Iodine", https://en.wikipedia.org/w/index.php?title=Lugol%27s_iodine&oldid=983526699, Creative Commons Attribution-ShareAlike License, Potassium triiodide, Lugol's solution, aqueous iodine, strong iodine solution, Lugol's iodine may also be used to better visualize the, Lugol's iodine may also be used as an oxidizing, This solution is used as an indicator test for the presence of, Lugol's solution can also be used in various experiments to observe how a, Lugol's solution is also used in the marine aquarium industry. The industrial preparation of HI involves the reaction of I2 with hydrazine, which also yields nitrogen gas:[5]. Contains 5% Iodine and 10% Potassium Iodide in aqueous solution. [citation needed]. Variations in the volume of a gas due to the pressure of aqueous vapor. Iodine is converted to iodide, which is trapped in the thyroid gland. Medical definition of Lugol's solution: any of several deep brown solutions of iodine and potassium iodide in water or alcohol that are used in medicine (as for the internal administration of iodine) and as microscopic stains —called also Lugol's iodine, Lugol's iodine solution. A.; Leito, I. Active substance(s): IODINE / POTASSIUM IODIDE, PDF options:  View Fullscreen   Download PDF. In this method, I2 reacts with phosphorus to create phosphorus triiodide, which then reacts with water to form HI and phosphorous acid: Solutions of hydrogen iodide are easily oxidized by air: HI3 is dark brown in color, which makes aged solutions of HI often appear dark brown. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. Identification Product Name Iodine, 0.1N standard solution Cat No. [11] However, it appears ineffective in patients who are already euthyroid on anti-thyroid drugs and levothyroxine. Date of first authorisation/renewal of the authorisation. "Acidities of strong neutral Brønsted acids in different media.". Continue typing to refine. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. [20] Other sources state that pure potassium iodide solution in water (SSKI) was eventually used for most of the thyroid protection after this accident. [22][failed verification], Historically, Lugol's iodine solution has been widely available and used for a number of health problems with some precautions. Lugol's solution provides a strong source of free iodine and iodide to reef inhabitants and macroalgae. Available for Android and iOS devices. [9] This reaction is an SN2 substitution, in which the iodide ion replaces the "activated" hydroxyl group (water): HI is preferred over other hydrogen halides because the iodide ion is a much better nucleophile than bromide or chloride, so the reaction can take place at a reasonable rate without much heating. Antonyms for strong iodine solution. In the United Kingdom the NHS pays £9.57 per 500 ml of solution. Lugol's iodine, also known as aqueous iodine and strong iodine solution, is a solution of potassium iodide with iodine in water. Antonyms for iodine. To view the changes to a medicine you must sign up and log in. Iodine Solution (0.02M in THF/pyridine/H 2 O 70:20:10) 1 Product Result | Match Criteria: Product Name "Viscosities of Aqueous Hydrochloric Acid Solutions, and Densities and Viscosities of Aqueous Hydroiodic Acid Solutions". [8], Lugol's iodine was first made in 1829 by the French physician Jean Lugol. 5.2 Pharmacokinetic properties. 4 synonyms for iodine: atomic number 53, I, iodin, tincture of iodine. The iodine in Lugol’s solution selectively binds to alpha-1,4 glucans found in polysaccharides, such as glycogen. Aqueous Iodine Solution may also be used for purposes not listed in this medication guide. Hydrogen iodide (H I) is a diatomic molecule and hydrogen halide. : SI86-1; SI86-4; T000861000 Synonyms No information available Recommended Use Laboratory chemicals. Aqueous solutions of HI are known as hydroiodic acid or hydriodic acid, a strong acid.Hydrogen iodide and hydroiodic acid are, however, different in that the former is a gas under standard conditions, whereas the other is an aqueous solution … Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group. Until 2007, in the United States, Lugol's solution was unregulated and available over the counter as a general reagent, an antiseptic, a preservative,[26] or as a medicament for human or veterinary application. Because of its wide availability as a drinking-water decontaminant, and high content of potassium iodide, emergency use of it was at first recommended to the Polish government in 1986, after the Chernobyl disaster to replace and block any intake of radioactive 131I, even though it was known to be a non-optimal agent, due to its somewhat toxic free-iodine content. But both are called "aqueous rocks," because they are formed under water. Another word for solution. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The code for attribution links is required. J Hosp.Infect. Sheep's wool does absorb (see Knowledge 191) the aqueous vapor. [12], Because it contains free iodine, Lugol's solution at 2% or 5% concentration without dilution is irritating and destructive to mucosa, such as the lining of the esophagus and stomach. Learn more. Iodine aqueous solution is given to render the thyroid firm and avoid the increased vascularity and friability with increased risk of haemorrhage that may result from the use of an antithyroid agent alone. Breton, G. W., P. J. Kropp, P. J.; Harvey, R. G. "Hydrogen Iodide" in Encyclopedia of Reagents for Organic Synthesis (Ed: L. Paquette) 2004, J. Wiley & Sons, New York. ... With Reverso you can find the English translation, definition or synonym for strong iodine solution and thousands of other words. The iodide combines with metallic iodine to form a high concentration of potassium triiodide (KI3) solution. Aqueous solution of iodine and potassium iodide Synonym: Schiller's test INSTRUCTIONS FOR USE REF Product code: LUG-OT-100 (100 mL) LUG-OT-250 (250 mL) LUG-OT-500 (500 mL) Introduction Lugol's solution, named after French physician J. G. A. Lugol, is widely used in the field of medicine. To email a medicine you must sign up and log in. [12], Except where otherwise noted, data are given for materials in their, Trummal, A.; Lipping, L.; Kaljurand, I.; Koppel, I. What are synonyms for strong iodine solution? The aqueous humour should not escape till the section is completed. [4][1] Long term use may result in trouble sleeping and depression. [16], The World Health Organization classifies substances taken orally with an LD50 of 5–50 mg/kg as the second highest toxicity class, Class Ib (Highly Hazardous). Find more ways to say solution, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. Qualitative and quantitative composition, 4.2 Posology and method of administration, 4.4 Special warnings and precautions for use, 4.5 Interaction with other medicinal products and other forms of interaction, 4.7 Effects on ability to drive and use machines, 6.6 Special precautions for disposal and other handling, 9. Another word for aqueous. Although harsh by modern standards, HI was commonly employed as a reducing agent early on in the history of organic chemistry. ‘Apply ethanol, tincture or aqueous solution of iodine, if available.’ ‘Norm was instantly on hand with all sorts of potions; antiseptic, iodine, everything.’ ‘Povidone-iodine is a solution commonly used if the patient is not allergic to iodine.’ ‘A vinegar and water douche is substituted for patients who are sensitive to iodine.’ Potassium iodide does not provide immediate protection but can be a component of a general strategy in a radiation emergency. 5.2 Pharmacokinetic properties. Find more ways to say aqueous, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. Iodine concentrations greater than 2.2% are subject to US regulations. Lugol's Solution is a 5 percent aqueous solution of iodine in combination with 10 percent potassium iodide. How to use this medicine Product Title (iodine, potassium iodide) 1. There are also minute quantities of carbon dioxide, aqueous vapour, and ammonia. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This supports a mechanism whereby I2 first dissociates into 2 iodine atoms, which each attach themselves to a side of an H2 molecule and break the H−H bond:[7]. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. • An allergy to iodine, iodides or any of the, We comply with the HONcode standard for trustworthy health information -. HI is subject to the same Markovnikov and anti-Markovnikov guidelines as HCl and HBr. It helps reduce the risk of bleeding during the operation. By continuing to browse the site you are agreeing to our policy on the use of cookies. [8] This process can be made catalytic in HI using red phosphorus to reduce the formed I2. In this example diethyl ether is split into ethanol and iodoethane: The reaction is regioselective, as iodide tends to attack the less sterically hindered ether carbon. [24][25] Only since the end of the Cold War has the compound become subject to national regulation in the English-speaking world. This solution is used in the treatment of many conditions in which the action of iodine ion is desired such as thyrotoxicosis, keratoscleritis, keratitis associated with excessive keratin. [17] The Global Harmonized System of Classification and Labeling of Chemicals categorizes this as Category 2 with a hazard statement "Fatal if swallowed".

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