The lymphatic system helps remove cellular waste, maintain fluid balance, and make and activate infection-fighting white blood cells for the immune system. The spleen may be affected by hyaloserositis, in which it is coated with fibrous hyaline. Splenomegaly can result from antigenic stimulation (e.g., infection), obstruction of blood flow (e.g., portal vein obstruction), underlying functional abnormality (e.g., hemolytic anemia), or infiltration (e.g., leukemia or storage disease, such as Gaucher's disease). The underlying central nervous processes coordinating the spleen's function seem to be embedded into the Hypothalamic-pituitary-adrenal-axis, and the brainstem, especially the subfornical organ.[14]. The spleen also plays an important role in traditional Chinese medicine and is the Yin part of the Earth element paired with its Yang counterpart the Stomach. The spleen can also become injured or rupture immediately after a hard hit to the abdomen, a rib fracture, or other accident. A ductless vascular gland, located in the left upper abdomen near the stomach. [12], The germinal centers are supplied by arterioles called penicilliary radicles.[13]. Your spleen is a small organ located on the left side of your abdomen under your rib cage. একটি সুসংগঠিত ও সুশৃঙ্খল প্রসূতি-হাসপাতাল যার মধ্যে তাৎক্ষণিক রক্ত সঞ্চালনের সুবিধা রয়েছে সেখানে নিয়মিত ভর্তি, মা এবং ভ্রূণের ভালমন্দের সতর্ক পর্যবেক্ষণ; এবং ৫. The spleen is an organ found in virtually all vertebrates.Similar in structure to a large lymph node, it acts primarily as a blood filter.The word spleen comes from Ancient Greek σπλήν (splḗn).. Healthline Media does not provide medical advice, diagnosis, or treatment. An enlargement of the spleen that leads to the destruction of too many blood cells is a condition called hypersplenism. [11], Maximum length of spleen on abdominal ultrasonography, Back of lumbar region, showing surface markings for kidneys, ureters, and spleen, Side of thorax, showing surface markings for bones, lungs (purple), pleura (blue), and spleen (green). In most vertebrates, the spleen continues to produce red blood cells throughout life; only in mammals this function is lost in middle-aged adults. Spleen removal surgery. Depending on your age and overall health, your doctor will likely recommend that you get vaccinated against infections like these: Though your spleen isn’t a large organ, it plays many important roles in your body. By using our services, you agree to our use of cookies. Hyposplenia refers to a partially functioning spleen. Your spleen is involved in your body’s immune response, and in recycling old blood cells. In chronic or critical cases, surgery may offer the best hope for recovery. You can live a normal, healthy life without a spleen. An enlarged spleen may not cause symptoms at first. The spleen is innervated by the splenic plexus, which connects a branch of the celiac ganglia to the vagus nerve. In English the word spleen was customary during the period of the 18th century. Polysplenia is a congenital disease manifested by multiple small accessory spleens,[25] rather than a single, full-sized, normal spleen. [7], In humans the spleen is purple in color and is in the left upper quadrant of the abdomen.[3][8]. [4], Transverse section of the spleen, showing the trabecular tissue and the splenic vein and its tributaries, Internal organ in most vertebrate animals, The human spleen is located in the upper left, Robertson's Word Pictures of the New Testament, commentary on 1 Peter 3:8, CS1 maint: multiple names: authors list (, "Identification of splenic reservoir monocytes and their deployment to inflammatory sites", "Immunology. Must I observe you? Phagocytosis needs natural antibodies, which are immunoglobulins that facilitate phagocytosis either directly or by complement deposition on the capsule. Encapsulated bacteria inhibit binding of complement or prevent complement assembled on the capsule from interacting with macrophage receptors. Both the short gastric arteries and the splenic artery supply it with blood. There are other openings present for lymphatic vessels and nerves. It also traps too many platelets. The spleen also stores red blood cells, platelets, and infection-fighting white blood cells. Avoid contact sports and other high-impact activities until cleared by your doctor. Assessment of IgM antibodies to viral capsid antigen (a rising titer) is indicated to confirm Epstein–Barr virus or cytomegalovirus. The spleen is 1 by 3 by 5 inches (3 by 8 by 13 cm), weighs approximately 7 oz (200 g), and lies between the 9th and 11th ribs on the left-hand side and along the axis of 10th rib. The spleen is part of your body’s lymphatic system. The left colic vein assists the body by draining old blood from the intestines. Although it can occur asymptomatically, the typical symptom is severe pain in the left upper quadrant of the abdomen, sometimes radiating to the left shoulder. While most of the gut organs are endodermally derived (with the exception of the neural-crest derived adrenal gland), the spleen is derived from mesenchymal tissue. Other functions of the spleen are less prominent, especially in the healthy adult: Enlargement of the spleen is known as splenomegaly. The sigmoid vein, also called the vena sigmoideus, refers to one group of sigmoid veins. It has been popularized by the poet Charles Baudelaire (1821–1867) but was already used before in particular to the Romantic literature (19th century). Similar in structure to a large lymph node, it acts primarily as a blood filter.

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