Menthol acts by blocking calcium channels and serotonin receptors in the muscles of the gut to relax smooth muscle and reduces symptoms of IBS. Epub 2019 Aug 27. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. doi: 10.1016/j.gtc.2010.12.006. (6), In a review by the British Medical Journal, almost 400 IBS patients were assigned either a peppermint oil capsule or a placebo. 2012;10(7):712–21.e4. 2020. Peppermint oil is extracted from the peppermint plant – a cross between water mint and spearmint. The Irritable Bowel Syndrome Out-come Study (IBSOS): rationale and design of a randomized, placebo-controlled trial with 12 month follow up of self-versus clinician-administered CBT for moderate to severe irrita-ble bowel syndrome. In the most comprehensive meta-analysis to date, PO was shown to be a safe and effective therapy for pain and global symptoms in adults with IBS. 2020 Jul 10;11:601. doi: 10.3389/fpsyt.2020.00601. (28), • Low FODMAP diet: this well-balanced diet that is catered to addressing the specific symptoms of IBS. https://pubmed.ncbi.nlm.nih.gov/21971535/, 27. Trinkley, K.E. Peppermint oil relaxes the muscles between the esophagus and the stomach, the lower esophageal sphincter, and worsen symptoms in people with gastroesophageal reflux disease (GERD). But you may wish to avoid taking peppermint oil at the same time as antacids – a type of indigestion medication. A randomized trial of yoga for adolescents with irritable bowel syndrome. However, there is no standardized dosage of peppermint oil, and studies looking at peppermint oil have evaluated various dosages. Oops! https://link.springer.com/article/10.1186/1710-1492-10-6, 21. Menthol-β-d-glucuronide: A potential prodrug for treatment of the irritable bowel syndrome. Lackner, J.M., Keefer, L., Jaccard, J., Firth, R., Brenner, D., Bratten, J., Dunlap, L.J., Ma, C., Byroads, M. and IBSOS Research Group, 2012. However, in rare cases, peppermint oil may cause heartburn or an allergic reaction. and Friend, D.R., 1994. Can peppermint oil help with IBS? https://research.monash.edu/en/publications/a-diet-low-in-fodmaps-reduces-symptoms-of-irritable-bowel-syndrom. Since IBS is aggravated by stress and anxiety, lifestyle changes and psychological therapies may be of value such as: • Gut-directed hypnotherapy: a form of guided entry into a state of deep relaxation with suggestions to alleviate bowel pain and discomfort. The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. Bmj, 337, p.a2313.  Recent studies have shown that peppermint oil can help relieve common IBS symptoms like pain and bloating. and Ernst, E., 1998. Some people may respond better to other types of antispasmodic medication. Herbal Therapies in Functional Gastrointestinal Disorders: A Narrative Review and Clinical Implication. Peppermint oil is generally considered safe in low doses, but it’s not for everyone. • Cognitive-behavioral therapy (CBT): this form of therapy involves retraining the mind to perceive sensations of the gut as normal, and to respond to thoughts positively. Nundy, S., 2017. You Q, Li L, Chen H, Chen L, Chen X, Liu Y. Clin Transl Gastroenterol. An active ingredient in peppermint oil, menthol, is believed to reduce pain by acting on the smooth muscles of the gut. In one study, participants who practiced yoga three times per week reported less severe symptoms and reduced anxiety. The most extensive review peppermint oil included data from over 800 patients from twelve clinical trials. PRISMA flowchart illustrating the process for the…, NLM We work with experts to ensure our content is helpful, accurate and trustworthy. and Saeidi, M.A.S.U.M.E.H., 2014. http://www.indianjournals.com/ijor.aspx?target=ijor:rjpt&volume=8&issue=7&article=024, 5. (5). Essential plant oils and headache mechanisms. 2014 Jul;48(6):505-12. doi: 10.1097/MCG.0b013e3182a88357. (21), Peppermint does not interact with most drugs. Peppermint oil has been used for centuries as a lip balm, toothpaste, and cold remedy but recent evidence shows that it is useful for irritable bowel syndrome (IBS). American family physician, 75(7), pp.1027-1030. 2019. Cochrane Database Syst Rev. doi: 10.1016/j.cgh.2012.02.029. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.935.3771&rep=rep1&type=pdf, 14. Lindfors, P., Unge, P., Arvidsson, P., Nyhlin, H., Björnsson, E., Abrahamsson, H. and Sim-rén, M., 2012. Peppermint oil: a treatment for postoperative nausea. and Nahata, M.C., 2014. Take control of how you think, feel and act. Plus free science-backed guides, infographics and whitepapers. doi: 10.5056/jnm16214. We performed random-effects meta-analysis on primary outcomes including global improvement in IBS symptoms and abdominal pain. that peppermint oil is a safe and effective short-term treatment for IBS. (27), • Yoga: this ancient practice combines physical and mental practices to strengthen the mind-body connection. Peppermint oil is extracted from the peppermint plant – a cross between water mint and spearmint. American Journal of Gastroenterolo-gy, 107(2), pp.276-285. Effect of fibre, antispasmodics, and peppermint oil in the treat-ment of irritable bowel syndrome: systematic review and meta-analysis. Talk with your doctor before you start using peppermint for IBS. The number needed to treat with PO to prevent one patient from having persistent symptoms was three for global symptoms and four for abdominal pain. -. Peppermint oil is a potent antimicrobial agent, so it fights IBS due to stomach issues. Alam, M.S., Roy, P.K., Miah, A.R., Mollick, S.H., Khan, M.R., Mahmud, M.C. -, Choung RS, Locke GR., 3rd Epidemiology of IBS. Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product De-rivatives, 20(8), pp.619-633. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337770/, 7. Research Journal of Pharmacy and Technology, 8(7), pp.929-931. https://www.bmj.com/content/337/bmj.a2313, 8. Today, peppermint is promoted for irritable bowel syndrome (IBS), other digestive problems, the common cold, sinus infections, headaches, and other conditions. But as suggested by the authors, this negative result may be due to the small sample of 190 patients. https://www.sciencedirect.com/science/article/pii/S1551714412001929?casa_token=1gfmC3ujh0YAAAAA:SqVDEk_fc5_URMfWty4Qu18sQzfTI1K9prkhjwc3ew-DuMl-Jcj_XE3V9tAVPYCu2qOYHhNZ, 28. Ask your doctor if you’re considering taking peppermint oil to help treat IBS symptoms. In addition peppermint oil also contains antimicrobial, anti-inflammatory, antioxidant, immunomodulating, and anesthetic activities, all of which may be relevant for the treatment of IBS. 89% of users report improved gut symptoms, Manage feelings of anxiety, stress & depression, 89% of users report improved gut symptoms. Background: Peppermint oil (PO) has intrinsic properties that may benefit patients with irritable bowel syndrome (IBS) symptoms. Something went wrong while submitting the form. Get the latest research from NIH: https://www.nih.gov/coronavirus. These include the antidepressant amitriptyline (Elavil) and the statin simvastatin (Zocor). Results: Effects of gut-directed hypnotherapy on IBS in different clinical settings—results from two randomized, controlled trials. CBT has been shown to help reduce the perception of pain in IBS. The capsule contains an enteric coat that prevents the acid of the stomach from breaking it down. 2008 May;30(5):884-901. doi: 10.1016/j.clinthera.2008.05.002. Regarding abdominal pain, the RR from six RCTs for the effect of PO (n = 278) versus placebo (n = 278) was 1.78 [95% CI: 1.43, 2.20], I2 = 0%, z = 5.23 (p < 0.00001). Peppermint oil for IBS reduces nausea, pain, gas, discomfort, bloating, and colon hypersensitivity. https://pubmed.ncbi.nlm.nih.gov/24267417/, 20. Join our newsletter and stay up to date on the latest articles on the mind-body connection, digital health and more. https://link.springer.com/article/10.1186/1746-4358-2-7, 26. [online] Available at: [Accessed 11 July 2020].

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