View abstract. Biol Trace Elem Res 2000;77:193-7.. View abstract. Some scientists think that germanium might decrease how well furosemide (Lasix) works. View abstract. Fukuoka Igaku Zasshi 1992;83(3):139-143. In closing, what can be said about germanium? Just from this breakdown, it is very clear that germanium is a useful and highly exploited element. Information from this source is evidence-based and objective, and without commercial influence. McMaster, M. L., Greco, F. A., Johnson, D. H., and Hainsworth, J. D. An evaluation of combination 5-fluorouracil and spirogermanium in the treatment of advanced colorectal carcinoma. 6-22-1991;135(25):1134-1137. https://www.accessdata.fda.gov/cms_ia/importalert_139.html. 1985;29(1):65-74. Germanium is LIKELY UNSAFE when taken by mouth in elemental form and in the form of certain compounds such as germanium oxide and germanium lactate-citrate. To learn more, visit our Earning Credit Page. A phase II study of spirogermanium in advanced human malignancy. Long, Q. C., Zeng, G. X., and Zhao, X. L. Pharmacokinetics of germanium after po beta-carboxyethylgermanium sesquioxide in 24 Chinese volunteers. Chest 2000;117:591-3.. View abstract. Kidney Int 2000;57:2275-84.. View abstract. Becker BN. Tubulointerstitial nephropathy persisting 20 months after discontinuation of chronic intake of germanium lactate citrate. Toxicology 1999;132:147-53.. View abstract. Krapf R, Schaffner T, Iten PX. Hess B, Raisin J, Zimmermann A, et al. View abstract. View abstract. View abstract. J.Altern.Complement Med. The appropriate dose of germanium depends on several factors such as the user's age, health, and several other conditions. Nephron 1992;60:436-42.. View abstract. Goodman S. Therapeutic effects of organic germanium. Ettinger DS, Finkelstein DM, Donehower RC, et al. J.Toxicol.Sci. Ming, X., Yin, H., and Zhu, Z. Phase I trial of spirogermanium given by infusion in a multiple-dose schedule. Uses of Germanium. Aso, H., Suzuki, F., Yamaguchi, T., Hayashi, Y., Ebina, T., and Ishida, N. Induction of interferon and activation of NK cells and macrophages in mice by oral administration of Ge-132, an organic germanium compound. View abstract. To unlock this lesson you must be a Study.com Member. J Vet.Med.Sci. Germanium is LIKELY UNSAFE when taken by mouth in elemental form and in the form of certain compounds such as germanium oxide and germanium lactate-citrate. 1990;54:53-60.. View abstract. Hirayama, C., Suzuki, H., Ito, M., Okumura, M., and Oda, T. Propagermanium: a nonspecific immune modulator for chronic hepatitis B. J Gastroenterol. Nephron 1992;60:436-42.. View abstract. 1996;17(5):415-418. Mutat Res 1997;387:141-6.. View abstract. Insufficient Evidence to Rate Effectiveness for... Vitamin D Deficiency: How Much Vitamin D Is Enough? In fact, the Mars Exploration Rovers contain germanium in their solar … Schweiz.Med.Wochenschr. View abstract. View abstract. Jpn.J.Med. J Toxicol Environ Health A 1999;58:289-97.. View abstract. Matsusaka T, Fujii M, Nakano T, et al. For example, metalloids typically appear metallic to the naked eye. View abstract. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Schweiz.Med.Wochenschr. 1991;30(1):67-72. Phase I clinical trial of spirogermanium. Kumano, N., Ishikawa, T., Koinumaru, S., Kikumoto, T., Suzuki, S., Nakai, Y., and Konno, K. Antitumor effect of the organogermanium compound Ge-132 on the Lewis lung carcinoma (3LL) in C57BL/6 (B6) mice. Van der Spoel, J. I., Stricker, B. H., Schipper, M. E., de Bruijn, W., de Smet, P. A., and Esseveld, M. R. [Toxic damage of kidney, liver and muscle attributed to the administration of germanium-lactate-citrate]. Suzuki, F. and Pollard, R. B. Eur.J Haematol. 1967;20(4):211-224. It might also have antioxidant properties and affect the immune system. A phase II study of spirogermanium in advanced human malignancy. 2002;64(8):719-721. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Luck, B. E., Mann, H., Melzer, H., Dunemann, L., and Begerow, J. Renal and other organ failure caused by germanium intoxication. Dis.Colon Rectum 1990;33(2):99-104. View abstract. Not sure what college you want to attend yet? Effect of organic germanium compound (Ge-132) on experimental osteoporosis in rats. Schroeder, H. A. and Balassa, J. J. Abnormal trace metals in man: germanium. Hess B, Raisin J, Zimmermann A, et al. Germanium might decrease how well furosemide (Lasix) works. Biotherapy 1991;3(3):273-279. 1996;34(4):221-223. Create your account, Already registered? Germanium-74 is the most abundant isotope while germanium-76 is the least abundant. J Toxicol Environ Health A 1999;58:289-97.. View abstract. Eur.J Haematol. View abstract. Regul Toxicol Pharmacol 1997;25:211-9. Protective role of germanium-132 against paraquat-induced oxidative stress in the livers of senescence-accelerated mice. Fujii, A., Kuboyama, N., Yamane, J., Nakao, S., and Furukawa, Y. Germanium have five naturally occurring isotopes: germanium-70, germanium-72, germanium-73, germanium-74 and germanium-76. Schein PS, Slavik M, Smythe T, et al. Acta Physiol Pol. Tao SH, Bolger PM. Hazard assessment of germanium supplements. Fukuoka Igaku Zasshi 1992;83(3):139-143. Hirayama, C., Suzuki, H., Ito, M., Okumura, M., and Oda, T. Propagermanium: a nonspecific immune modulator for chronic hepatitis B. J Gastroenterol. View abstract. Hirayama, C., Suzuki, H., Ito, M., Okumura, M., and Oda, T. Propagermanium: a nonspecific immune modulator for chronic hepatitis B. J Gastroenterol. View abstract. Phase II study of spirogermanium in advanced ovarian malignancy. 1986;8(5):379-386. Renal and other organ failure caused by germanium intoxication. View abstract. View abstract. Jao, S. W., Lee, W., and Ho, Y. S. Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats. Log in here for access. J Interferon Res 1984;4(2):223-233. Scientific error and misrepresentation. View abstract. Woolley, P. V., Ahlgren, J. D., Byrne, P. J., Priego, V. M., and Schein, P. S. A Phase I trial of spirogermanium administered on a continuous infusion schedule. Gerber GB, Leonard A. Mutagenicity, carcinogenicity and teratogenicity of germanium compounds. Nakada, Y., Kosaka, T., Kuwabara, M., Tanaka, S., Sato, K., and Koide, F. Effects of 2-carboxythylgerumanium sesquioxide (Ge-132) as an immunological modifier of post-surgical immunosuppression in dogs. Biotherapy 1991;3(3):273-279. Tohoku J Exp.Med. View abstract. Budman DR, Schulman P, Vinciguerra V, Degnan TJ. Cancer Treat.Rep. Henry, M. C., Rosen, E., Port, C. D., and Levine, B. S. Toxicity of spirogermanium in mice and dogs after iv or im administration. Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): an Eastern Cooperative Oncology Group study. At this time there is not enough scientific information to determine an appropriate range of doses for germanium. As both the germanium and germanium oxides are transparent to infrared radiation, these are used in infrared spectroscopes. Ginseng-induced diuretic resistance. View abstract. Study.com has thousands of articles about every A typical daily diet includes 0.4-3.4 mg of germanium. View abstract. Fujimoto, M., Ishibashi, H., Shimamura, R., Takahashi, K., Hirata, Y., Kudo, J., Niho, Y., Kira, J., and Miyata, K. [A patient with liver cirrhosis manifesting various symptoms including cerebellar ataxia due to germanium intoxication]. Biotechnol.Appl.Biochem. imaginable degree, area of 2004;73(6):397-401. Gan To Kagaku Ryoho 1984;11(6):1303-1306. Pure germanium is a semiconductor with an appearance similar to elemental silicon. Visit the AP Chemistry: Help and Review page to learn more. 2010 Minerals Yearbook: Germanium. You are encouraged to report negative side effects of prescription drugs to the FDA. View abstract. Dis.Colon Rectum 1990;33(2):99-104. View abstract. Eur.J Haematol. How Long Does Coronavirus Live On Surfaces? 1999;14(10):2464-2468. Ming, X., Yin, H., and Zhu, Z. DiMartino, M. J., Lee, J. C., Badger, A. M., Muirhead, K. A., Mirabelli, C. K., and Hanna, N. Antiarthritic and immunoregulatory activity of spirogermanium. Invest New Drugs 1984;2(3):305-309. Accessed Jan. 7, 2019. 1991;30(1):67-72. View abstract. Some people use germanium for osteoarthritis, … Prevention of suppressed interferon gamma production in thermally injured mice by administration of a novel organogermanium compound, Ge-132. J.Altern.Complement Med. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. Kumano, N., Ishikawa, T., Koinumaru, S., Kikumoto, T., Suzuki, S., Nakai, Y., and Konno, K. Antitumor effect of the organogermanium compound Ge-132 on the Lewis lung carcinoma (3LL) in C57BL/6 (B6) mice. Phase I trial of spirogermanium given by infusion in a multiple-dose schedule. View abstract. Shim, J. U. and Lim, K. T. Antioxidative activity of glycoprotein isolated from Geranium sibiricum Linne. Int.J Clin.Pharmacol Ther.Toxicol. View abstract. Learn more about Germanium uses, benefits, side effects, interactions, safety concerns, and effectiveness. Kidney Int 2000;57:2275-84.. View abstract. Hepatitis B. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Aso, H., Suzuki, F., Yamaguchi, T., Hayashi, Y., Ebina, T., and Ishida, N. Induction of interferon and activation of NK cells and macrophages in mice by oral administration of Ge-132, an organic germanium compound. [Effect of dietary selenium and germanium on the precancerous lesion in rat glandular stomach induced by N-methyl-N'-nitro-N-nitrosoguanidine]. Mutat Res 1997;387:141-6.. View abstract. Kleinrok, Z., Lekim, D., and Jagiello-Wojtowicz, E. Central action of sanumgerman administered orally in mice. Ikemoto, K., Kobayashi, M., Fukumoto, T., Morimatsu, M., Pollard, R. B., and Suzuki, F. 2-Carboxyethylgermanium sesquioxide, a synthetic organogermanium compound, as an inducer of contrasuppressor T cells. Vogelzang NJ, Gesme DH, Kennedy BJ. View abstract. 's' : ''}}. Insufficient Evidence to Rate Effectiveness for... Next to red peppers, you can get the most vitamin C from ________________. Harefuah 11-16-1997;133(10):446-7, 502. J.Altern.Complement Med. Mrema, J. E., Slavik, M., and Davis, J. Spirogermanium: a new drug with antimalarial activity against chloroquine-resistant Plasmodium falciparum. Kleinrok, Z., Lekim, D., and Jagiello-Wojtowicz, E. Central action of sanumgerman administered orally in mice. The element is mostly distributed in nature, but it’s too reactive to occur free. Create an account to start this course today. © 2005 - 2019 WebMD LLC. Acta Physiol Pol. View abstract. Kaplan, B. J., Andrus, G. M., and Parish, W. W. Germane facts about germanium sesquioxide: II. Raisin, J., Hess, B., Blatter, M., Zimmermann, A., Descoeudres, C., Horber, F. F., and Jaeger, P. [Toxicity of an organic Germanium compound: deleterious consequences of a "natural remedy"].

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