n-Butyl acetate. Nelson KW, Ege JF, Ross M, Woodman LE, Silverman L [1943]. tert-Butyl acetate (TBAc) is an industrial chemical with potential uses as a degreaser and in architectural coatings. hޔͽ In: Documentation of the threshold limit values and biological exposure indices. Yakkyoku (Pharmacy) [1981]; 32(10):1241-1247 (in Japanese). LC50 Determination of tert-Butyl Acetate using a Nose Only Inhalation Exposure in Rats. Get the latest public health information from CDC: https://www.coronavirus.gov. Smyth HF Jr [1956]. 53 0 obj <>stream 5. Harmful if inhaled. ,�իsN�5H�. Human health screening level risk assessments of tertiary-butyl acetate (TBAC): calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations. Centers for Disease Control and Prevention. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Bethlehem, PA: National Printing Ink Research Institute, p. 7. EPA [1987]. Environmental Toxicity: n-Butyl acetate. Yang YS, Ahn TH, Lee JC, Moon CJ, Kim SH, Park SC, Chung YH, Kim HY, Kim JC. Grant WM [1974]. This site needs JavaScript to work properly. n-Butyl acetate: acute vapor inhalation toxicity test in rats. Vapor concentrations may cause drowsiness. TBA has been shown to induce tumors in both rats and mice, and the Office of Environmental Health Hazard Assessment has calculated an oral cancer potency factor (CSF) for TBA of 3 x 10(-3)(mg/kg-day)(-1). NLM m�Z �0�W�.�6)� }��D��O�ʠfœ���!��!�Z��(� `�l�s���8� �oEq����9�e�%}z�o�_5_����� ACGIH [1971]. Additionally, TBAc has been demonstrated to be substantially metabolized … When released into the air , this material may be moderately degraded by reaction with photochemically produced hydroxyl radi cals. Causes skin and eye irritation. endstream endobj 4 0 obj <> endobj 12 0 obj <>stream 2007. Improved communication: hygienic standards for daily inhalation. Therefore, TBAc should be considered to pose a potential cancer risk to humans because of the metabolic conversion to TBA. application/pdf 1. 2nd ed. Epub 2012 Sep 7. 4. Limited chronic toxicity data exist for TBAc. Chemical Name Concentration (%) 123-86-4 n-Butyl acetate 90 - 100 Molecular formula : C6-H12-O2 SECTION 4. 6th ed. 2016-02-26T11:36:03-05:00 2007 Oct;80(5):374-82. doi: 10.1002/bdrb.20124. Show this safety data sheet to the doctor in attend- ance. Springfield, IL: C.C. 2010 Dec;26(4):293-300. doi: 10.5487/TR.2010.26.4.293. n-Butyl acetate. Arch Gewerbepath Gewerbehyg 5:1-90 (in German). 2006 Dec;46(3):243. 6. �BΒ���ֺ3R�l%j��m�}]��D�����Q+B�P o#E�Kwo�8�N�X�7��!G&]L6����0 A"x� endstream endobj 1 0 obj <> endobj 2 0 obj <>stream Vapors may cause flash fire or explosion. Toxicol Res. ��*0)a���uŠB��KuS����xbS���/��ęx�ek��e�g�~ٓ�X�[W�"�Ek��I�lAܞ'����X�%��Ɋ���ʶc���ݟw�_v�J�Gڐ���ruN�d9�^ԳO�#-��DV?��œ��ԭC�l%��K�^��dۭ4��Z.�b�~΁�e+��f���^!.Y���-����m0�~�?ك�]J���:$�x���i$�hdܚFb#�yk���)�2/��`Z^q��YA8CMi쵠.�0iZ�u ��F#4Z1@M�m;��Z)��4��X-�ت� �#���^���s�kX�=���(��E�$�� �1��yʤ�L�v��H�Q��,tڴ��"U�jDP}RRF3�ڂ;��A9 H���n�H���,�hd�Eޠ_@��A��"���*��w3�4�,���F�^�f�G��s���d�VҒ;��h�T?��w� �tt������T�7q�e��*��a���.M�����c���I'��~�?���"�H��ҿ��$'kg㯵a�w/^K��Sty8:�uqD"�����K8*��V���!��6�yW*��V��I�LW|�v��D��R��S�5QRE�߅FCi��A6Uqh�뺊D"�N����p�x�� �q">Zj��$x7�u�E"�h��� hC$�Y�ָ�y[���bz��>��a\��}])]�l��T�mw�8D"�h�j)�Fiw="��˓��E+-���,���I���wU?�K^�$�����E"�c�����ʹ��Ż6aR09���`)-��g� *NA�lʆK�1L�������m@���,?Q�'_Bx�_8?����?t��_˓Z~��4n��4g�e� �h6�Ro,]�B:����ۧ���c�!�WM��wN��p���4�-�F��&&EN*u�ʹ4�~e�N��9������М��U:��Q��z�O����Q�B؈w%��ށ�#W��0Pˣ���l��M�1�8���C�LyS��(�lz�|ȱ��E�zkn�v-B,� ;Tbjm�C��FN~�By�Le��?�;���l �%�/�wb��5gl�L�;*;�%N��w�����+��K��Fҧz^�V�������$���9��z�������@�ǃ(S[��=��G� nQQ� endstream endobj 13 0 obj <>stream Crit Rev Toxicol. HAZARDS IDENTIFICATION Danger! 3 / 17 BUTYL ACETATE Safety Data Sheet BUTYL ACETATE Version 1.0 Date: 06/01/2015 Hazardous components CAS-No. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Anderson SE, Franko J, Anderson KL, Munson AE, Lukomska E, Meade BJ. Regul Toxicol Pharmacol. An inhalation unit risk value for TBAc of 4 x 10(-7)(microg/m(3))(-1) can then be derived from the CSF value for TBAc by assuming a human breathing rate of 20 m3/day, 70% fractional absorption, and an average human body weight of 70 kg.

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